Cetamol Cold and Flu nighttime multi-symptom. relief fast and effective relief of nasal and sinus. congestion, pain, and fever. cough and sore throat allergy, runny nose, sneezing, itchy and watery eyes. aspirin free caffeine-free. Painkillers like acetylsalicylic acid (ASA ? the drug in medicines such as Aspirin), ibuprofen and acetaminophen (paracetamol) can relieve cold-related symptoms such as headache, earache and joint pain. These painkillers can also lower a fever.?They don’t help to relieve a cough or stuffy nose.